Pharma All-in-One

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Showing posts with label Pharma Concepts. Show all posts
Showing posts with label Pharma Concepts. Show all posts

Friday, March 08, 2019

Immunology | immunity | Innate (non-specific) and Adaptive (specific) immunity


Introduction

Immunity or resistance is the ability to ward off damage or disease through our defenses
The two general types of immunity
ü  Innate (nonspecific) immunity refers to defenses that are present at birth.  Among the components of innate immunity are the first line of defense (the physical and chemical barriers of the skin and mucous membranes) and the second line of defense (antimicrobial substances, natural killer cells, phagocytes, inflammation, and fever).
ü  Adaptive (specific) immunity refers to defenses that involve specific recognition of a microbe once it has breached the innate immunity defenses. Adaptive immunity is based on a specific response to a specific microbe; that is, it adapts or adjusts to handle a specific microbe. Adaptive immunity involves lymphocytes (a type of white blood cell) called T lymphocytes (T cells) and B lymphocytes (B cells).


Tuesday, March 05, 2019

Cardiovascular System (CVS) | Anti-hypertensive agents | Mechanism of action

Anti-hypertensive agents

Hypertension is defined as a sustained diastolic blood pressure greater than 90 mm Hg accompanied by an elevated systolic blood pressure (>140 mm)

Sunday, March 03, 2019

Pharmacology (Basics): Mechanism of drug action



Pharmacology (Basics): Mechanism of drug action


Mechanism of drug action:

Four major bio-molecular targets:
  1. Enzymes
  2. Ions channels
  3. Transporter or carrier molecules
  4. Receptors